PMLS 2019 EAST2019-04-19T12:28:42+00:00
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The Precision Medicine Leaders Summit is proud to partner with one of the most prestigious and the oldest medical schools in the United States, The Perelman School of Medicine at the University of Pennsylvania.  The UPenn School of Medicine provides the perfect backdrop to continue the discussion on the implementation of Precision Medicine, across not only large research institutions, but community settings where up to 85% of patients currently receive treatment.

Building on the successes of our events in San Diego and Jersey City, we hope you will join us for the most thought-provoking Precision Medicine event in the marketplace. Our speakers cover the panoply of leaders in the healthcare continuum, these include clinicians, industry experts, academics, regulators, payers, genetic counselors, bioinformaticians, and many more who are shaping the way Precision Medicine is implemented into healthcare systems on a global scale.

Join us for panel discussions, keynotes, roundtables, networking, exhibits, and opening reception to hear from thought leaders who are making the promise of Precision Medicine a reality.

REGISTER TODAY

PLATINUM PARTNER

Bristol-Myers Squibb

DIAMOND PARTNER

Thermo Fisher Scientific

FLAGSHIP PARTNERS

XIFIN, Inc.
Visual Strata
Genome Medical
Seimens
Penn Medicine
SomaLogic
University of Arizona
Roche
Trapelo
Genentech

AGENDA

TUESDAY JUNE  11th, 2019

7:15-8:00am

Registration & Breakfast Buffet

8:00-8:10am

Welcome and Opening Remarks

David Roth, MD, PhD, Simon Flexner Professor and Chair of Pathology and Laboratory Medicine, Director, Penn Center for Precision Medicine, University of Pennsylvania Perelman School of Medicine

Nigel Russell, Founder & President, The Journal of Precision Medicine and the Precision Medicine Leaders Summits.

8:10-8:40am

Keynote – Stay Tuned – TBD

8:45-9:35am

Immunotherapies and their Impact on Precision Medicine

9:40–10:30am

Advancing Precision Health with Approaches that Leverage Previously Unconnected Biomolecular and Clinical “Big Data”

Moderator: Yves A. Lussier, MD, FACMI, Associate Vice President for Health Sciences and Chief Knowledge Officer
Executive Director, Center for Biomedical Informatics and Biostatistics University of Arizona Health Sciences

Panelists: Jason H. Moore, PhD, FACMI, Edward Rose Professor of Informatics,Director, Institute for Biomedical Informatics,Director, Division of Informatics, Department of Biostatistics, Epidemiology, & Informatics,Senior Associate Dean for Informatics ,The Perelman School of Medicine University of Pennsylvania, Lara Mangravite, PhD, President, Sage Bionetworks, Michael Cantor, MD, MA, Executive Director, Clinical Informatics, Regeneron Genetics Center

The availability of Big Data across multiple dimensions, from electronic health records, lifestyles, environmental factors, genetics, to genomics, presents diverse challenges for existing informatics technology, in terms of computational efficiency, modeling effectiveness, statistical computing, discovery algorithms, and heterogeneous data integration. A growing trend is the creative integration of data collected independently for different purposes often not sharing common identifiers to enable novel analytical inferences unfeasible from smaller datasets. For example, novel toxidromes may be unveiled from jointly analyzing pollution data geospatially across different domains (i.e., air, land, and water) with clinical data. This panel will discuss analytics in the field of translational bioinformatics that strives to bridge the gap between disciplines among statistical genetics, clinical informatics, and bioinformatics as well as previously unconnected datasets (e.g., Emerge, GTEx, GEO, All of Us, UK Biobank, DrugBank), to advance precision health.

10:30–11:00am

Coffee & Networking

 11:00- 11:20am

Promises, Promises & Precision Medicine

Michael Joyner, MD, Chair for Research, Department of Anesthesiology, Frank R. and Shari Caywood Professor of Anesthesiology,  Distinguished Mayo Investigator

The Precision Medicine (PM) narrative flowed from the widely anticipated “Genetic Revolution in Medicine” that was pitched as a follow on to the Human Genome Project. In this talk I will deconstruct the PM narrative, highlight its limitations and ask critical questions about its continued viability. I will provide numerous examples of how the PM narrative has underperformed and discuss reasons why – beyond some niche applications – it is unlikely to transform human health in the future. Based on the limitations of PM, a vigorous debate about the future of the biomedical research and health policy agendas are urgently needed.

11:20–12:10pm

Pharmacogenomics Role in Precision Medicine

Moderator: Philip Empey, PharmD, PhD, Associate Director of the Institute of Precision Medicine at the University of Pittsburgh and UPMC

Panelists: Peter Silvester, Senior Vice President and President, Life Sciences Solutions, Thermo Fisher Scientific

12:10–1:00pm

LUNCH

1:00– 1:30pm

Update on All of Us Program

Stephanie Devaney, PhD, Deputy Director, All of Us Research Program, NIH

The All of Us Research Program is a key element of the Precision Medicine Initiative (PMI). Through advances in research, technology, and policies that empower patients, the PMI will enable a new era of medicine in which researchers, health care providers, and patients work together to develop individualized care.

PMI launched in fiscal year 2016 when $130 million was allocated to NIH to build a national, large-scale research participant group, called a cohort, and $70 million was allocated to the National Cancer Institute to lead efforts in cancer genomics as part of PMI for Oncology.

1:35 – 2:25pm

Precision Medicine Clinical Trials and Novel Designs: Levering Data, ‘Omics’, AI and Policy

Moderator: Arturo Loaiza Bonilla, MD, MSEd, FACP, Vice Chair, Department of Medical Oncology, CTCA

Panelists: Julia A. Beaver, MD, Director of the Division of Oncology Products 1 (DOP1) Office of Hematology and Oncology Product, FDA, Richard Schilsky, MD, FACP, FASCO, FSCT, Senior Vice President and Chief Medical Officer, ASCO, Gary Palmer, MD, Chief Medical Officer, Selin Kurnaz, PhD,  CEO – Massive Bio

The paradigm changes from the ‘phenotype-to-genotype’ to the ‘genotype-to-phenotype’ approach has revolutionized R&D and Clinical trials in oncology and other diseases. This panel will discuss the impact of novel approaches to clinical trial design, including the use of technology, biomarker data and the current regulatory landscape which is moving the needle forward in earlier access and approval of promising compounds. The audience will be able to learn further about ‘basket’, ‘umbrella’, ‘seamless’, ‘adaptive’ design trials, synthetic control arms, ‘Just-In-Time (JIT) trials, as will have the opportunity to how different stakeholders are adapting to recent FDA policies and regulations for their R&D and clinical trial matching enrollment.

2:30–3:30pm

Biomarkers to Predict Response and Resistance to Targeted and Immunotherapies

Moderator: Nic Dracopoli, 

Panelists: Timothy Chan MD, PaineWebber Chair in Cancer Genetics; Director, Immunogenomics and Precision Oncology Platform; Member, Human Oncology & Pathogenesis Program; Vice Chair, Department of Radiation Oncology; Director, Translational Oncology Division, Ilan “Lanny” Kirsch, M.D. Senior Vice President of Translational Medicine, Adaptive Biotechnologies

Dracopoli – Predicting response to targeted and immunotherapies

Kirsch – Immunosequencing in the service of immune-oncology

Chan – Genetic determinants of immunotherapy efficacy and resistance

This session will provide an update on the current use of biomarkers to predict response to targeted and immunotherapies in the treatment of cancer patients. Speakers in the session will discuss latest developments of deep sequencing of the T-Cell receptor to look for clonal T-cell infiltration in tumors as evidence of a prior suppressed immune response, evaluation of individual somatic alterations driving response to targeted signal transduction inhibitors, and to evaluate tumor mutation burden and HLA Class I antigen presentation to predict response to checkpoint inhibitors.

3:30-3:45pm

Coffee & Networking

3:45- 4:35pm

Innovation in Genomic Medicine Implementation

Moderator: Erica Ramos, MS, LCGC President National Society of Genetic Counselors and Director of Business development, Geisinger National Precision Health.

Panelists: Erynn Gordon, MS, LCGC, VP of Clinical Operations, Genome Medical, Tara Schmidlen, MS, CGC, Clinical Investigator/Genetic Counselor, Geisinger Health System, Leslie Bucheit MS, CGC, Product Manager, Digital Products, Myriad Genetics

While the technology and knowledge driving precision medicine continue to press ahead, how do we assure real value is realized for the acute setting equitably and at scale – and for populations, in context with fostering healthy communities. What are strategies to bridge the current landscape to a more harmonious future? What are we doing right? What will we regret? What will we laugh about? A panel of experts will have an honest assessment and share their vision for leaders in many facets of the field, from academia to industry to the community.

4:40 – 5:30pm

Improving Women’s Health Through Precision Care

Moderator: Amy Miller PhD, CEO – Society for Women’s Health Research

Panelists: Katie Johansen Taber, PhD, Director, Clinical Development Myriad Women’s Health, Damian P. Alagia III, MD, MS, MBA, FACS, FACOG, Medical Director for Women’s Health and Reproductive Medicine for Quest Diagnostics

Women have historically been underrepresented in health research, leading to care that may be suboptimal for their needs. This panel will discuss the current landscape of women’s health care, opportunities and challenges for drug and diagnostic development focused conditions specific to or more prevalent in women, optimizing the delivery of care for women, and the market opportunity for continued investment in research and development related to women’s health.

5:35-6:45pm

Roundtables

7:00-9:00pm

Networking Reception at Penn Museum (China & Egypt Exhibits) – enjoy drinks and hors d’houvres with fellow attendees, speakers and sponsors.

WEDNESDAY JUNE 12th, 2019

7:15-8:00am

Breakfast Buffet

8:00- 8:05am

Day One Recap

8:05-8:15am

Advancing Personalized Medicine Through Shared Value

Edward Abrahams, Ph.D. President, Personalized Medicine Coalition

8:15–8:45am

Keynote: Grace Cordovano, Ph.D.

8:50–9:40am

Gene Editing – The Breakthrough Technology

Moderator: Eric Kmiec, PhD, Director, Gene Editing Institute, Center for Translational Cancer Research, Helen F. Graham Cancer Center and Research Institute, Christiana Care Health System

Panelists: Lorenz Mayr, PhD, Chief Technology Officer, GE Healthcare, Ben Zeskind, PhD, MBA, Co-Founder and CEO, Immuneering Corporation.

CRISPR-directed human gene editing, is a form of precision medicine that is considered to be a breakthrough technology. While certainly not alone in this space, transition from bench to bedside requires that these technologies, especially for therapeutic use, are not only reproducible but robust. This line of thinking means that outstanding technological advances made in top laboratories around the world with unlimited resources are viewed as exciting and dramatic science. But, unless these technologies can be carried out within a diverse patient population, they will have little impact on patient care and will not be delivered in an efficient fashion. A robust technology means that just about every location or caregiver can carry out the process and isn’t limited to specific sites around the country that have the highest degree of technological and service expertise.

9:45 – 10:05am

Immune Health

Robert Vonderheide, MD, DPhil, Director of the Abramson Cancer Center, John H. Glick Abramson Cancer Center Professor, Perelman School of Medicine, University of Pennsylvania

10:05 – 10:35am

Coffee & Networking

10:35-11:25am

Mind the Gap: Are Mutational Profiles Sufficient for Precision Medicine?

Moderator: John Quakenbush, PhD, Henry Pickering Walcott Professor of Computational Biology and Bioinformatics
Chair, Department of Biostatistics, TH Chan School of Public Health, Harvard 
University

Panelists: Benjamin Haibe-Kains, PhD,  Senior Scientist, Princess Margaret Cancer Centre (PM), University Health Network, and Associate Professor in the Medical Biophysics Department of the University of Toronto

Much of precision medicine has been built on the idea that we can match patients to appropriate therapies based on their genetic background or that of their disease. But despite the success of targeted therapies and their associated biomarkers, not every patient with or without the “predictive” mutation responds as expected to the associated therapy. This suggests that single biomarkers are not sufficient and argues for more sophisticated, network medicine approaches. This panel will explore the limits of current precision medicine strategies and the ways in which these might be extended to better match patients to the most appropriate therapy.

11:30am-12:20pm

Expanding Precision Medicine by Improving Diagnostic Accuracy

Moderator: Luis M. Lasalvia, MD, VP & Global Medical Officer, Siemens Healthineers

Panelists: Kenneth J. Pienta, M.D. The Donald S. Coffey Professor of Urology, Professor of Oncology, Professor of Pharmacology and Molecular Sciences, The Johns Hopkins Hospital. Dwight Raum, Vice President & Chief Technology Officer, The Johns Hopkins University and the Johns Hopkins Health System

12:20-1:10pm

LUNCH

1:15 –1:45pm

Public Health and Precision Medicine Working in Harmony

David B Nash, MD, MBA, Dean Jefferson College of Population Health, Dr. Raymond C. & Doris N. Grandon Professor of Health Policy, Thomas Jefferson University

1:50-2:40pm

Diagnostic and Clinical Data Integration: A Framework for Improving Quality of Care

Moderator: Lori Anderson, Product Marketing Manager, XIFIN, Inc

Panelists: Wendy Rubinstein, MD, PhD,  Deputy Medical Director, CancerLinQ, LLC, American Society of Clinical Oncology, Shawn Glisson, MD, Medical Hematologist/Oncologist, Norton Cancer Institute, Omar Perez, PhD, RAC, Head of Precision Medicine and Diagnostics R&D, GSK

Despite the advances in health care data interoperability, multimodal patient data remains trapped in disparate data systems creating access problems for clinicians and complicating information sharing between multidisciplinary teams. The promise of precision medicine is to improve the quality of patient care by leveraging diagnostic data to drive clinical treatment decisions that result in better patient outcomes. Breaking down data silos allows organizations to design, track and document new quality metrics for the purpose of continuously improving quality of care for clinicians as well as enabling the development of clinical evidence necessary to establish medical necessity, actionability and clinical utility for diagnostics.

2:45-3:05pm

Precision Oncology – How The “End of Average” Transforms Clinical Decision Making  

Okan Ekinci, MD, MBA, Chief Medical Officer – Roche Diagnostics Information Solutions

3:10–4:00pm

Molecular Tumor Boards Role in Precision Medicine

4:00-4:30pm

Coffee & Networking

4:30-4:50pm

Transforming Healthcare Through AI-driven Cinical Genomic Insights to Improve Patient Lives.

Charlene Son Rigby, MBA  CBO Fabric Genomics

Precision medicine promises customized patient therapy by maximizing treatment effectiveness and minimizing side effects. Genomics is a critical tool in making precision medicine a reality. With genomic testing becoming more mainstream within the U.S. and worldwide, clinical and hospital laboratories are starting to publish compelling data on its utility. Yet adoption continues to be hampered by cost. Technology advances are critical to lower costs and accelerate adoption. The importance of technology, automation and the role for AI in genomic data interpretation will be discussed along with patient examples including ending her family’s diagnostic odyssey through whole exome testing.

4:55-5:45pm

AI in Precision Medicine

5:45pm

Closing Remarks

SPEAKERS

Lori Anderson

Lori Anderson

Product Marketing Manager, XIFIN, Inc.

Lori Anderson is product marketing manager for precision medicine informatics at XIFIN, where she brings many years of experience in medical affairs and product portfolio management in the healthcare and life-sciences industries. Prior to joining XIFIN, Lori was the director of health economics and outcomes research at Quest Diagnostics where she defined the reimbursement strategy for numerous tests routinely used in precision medicine. As a laboratorian herself with a particular interest in hematological neoplasms and the role of platelets in cardiovascular disease, Lori has contributed to the publication of 10 book chapters, 20 peer reviewed publications and over 40 poster presentations and has presented on numerous topics in laboratory medicine and life sciences worldwide.

Glisson

Shawn Glisson, MD

Medical Hematologist/Oncologist, Norton Cancer Institute

Okan Ekinci is the Chief Medical Officer for Diagnostics Information Solutions (DIS) at F. Hoffmann La-Roche Ltd in Basel, Switzerland. He is a member of the leadership team of DIS, an organisation focused on decision support solutions, powered by aggregated data and advanced analytics, in support of Roche’s personalised healthcare (PHC) strategy. The goal is to redefine how data and analytics can drive patient care and R&D to help ensure the right treatment reaches the right patient.

Okan has 20+ years of experience in the healthcare sector, including 8 years of clinical practice in cardiology. Before joining Roche, he was Global Head & Vice President of the Healthcare Consulting business at Siemens Healthineers, developing and offering IT-enabled transformation and clinical consulting services. With his team he introduced data-driven innovative offerings such as Radiology Performance Management Services and 4D Workflow Simulation Services for healthcare institutions. Prior to that, he established the Global Medical Office of Healthineers and served as its first CMO, across imaging, in-vitro diagnostics and healthcare IT.

Okan is an adjunct Professor of Medicine at University College Dublin, Ireland, holds an MBA from the European School of Management and Technology, Berlin and an MD from University of Mainz, Germany. He’s an alumni of Harvard Business School‘s Value-based Healthcare program.

Okan

Okan Ekinci, MD, MBA

Chief Medical Officer, Roche Diagnostics Information Solutions

Okan Ekinci is the Chief Medical Officer for Diagnostics Information Solutions (DIS) at F. Hoffmann La-Roche Ltd in Basel, Switzerland. He is a member of the leadership team of DIS, an organisation focused on decision support solutions, powered by aggregated data and advanced analytics, in support of Roche’s personalised healthcare (PHC) strategy. The goal is to redefine how data and analytics can drive patient care and R&D to help ensure the right treatment reaches the right patient.

Okan has 20+ years of experience in the healthcare sector, including 8 years of clinical practice in cardiology. Before joining Roche, he was Global Head & Vice President of the Healthcare Consulting business at Siemens Healthineers, developing and offering IT-enabled transformation and clinical consulting services. With his team he introduced data-driven innovative offerings such as Radiology Performance Management Services and 4D Workflow Simulation Services for healthcare institutions. Prior to that, he established the Global Medical Office of Healthineers and served as its first CMO, across imaging, in-vitro diagnostics and healthcare IT.

Okan is an adjunct Professor of Medicine at University College Dublin, Ireland, holds an MBA from the European School of Management and Technology, Berlin and an MD from University of Mainz, Germany. He’s an alumni of Harvard Business School‘s Value-based Healthcare program.

Laura Beaver

Julia A. Beaver, MD

Director, Division of Oncology Products 1 (DOP1), Office of Hematology and Oncology Products, FDA

Julia A. Beaver, MD, is the Director of the Division of Oncology Products 1 (DOP1) in the Office of Hematology and Oncology Products at the U.S. Food and Drug Administration (FDA). She is also an Assistant Professor of Oncology, part-time, at Johns Hopkins University where she is a member of the Johns Hopkins Breast Cancer Group. Dr. Beaver serves on the Liquid Biopsy Blood Profiling Atlas in Cancer (Blood-PAC) committee and leads FDA’s next generation sequencing laboratory collaboration. Dr. Beaver graduated magna cum laude from Princeton University and then earned her medical degree from the University of Pennsylvania School of Medicine. She completed a residency in internal medicine at Johns Hopkins University School of Medicine, followed by a fellowship in medical oncology at The Johns Hopkins Sidney Kimmel Cancer Center.

Ken Pienta

Kenneth J. Pienta, M.D

The Donald S. Coffey Professor Urology, Director, Urology Research Laboratories, Professor Oncology, Pharmacology and Molecular Sciences, Chemical and Biomolecular Engineering

Kenneth J. Pienta is the Donald S. Coffey Professor of Urology and serves as the Director of Research at the Brady Urological Institute of the Johns Hopkins University School of Medicine. He is also a Professor in the Departments of Oncology and Pharmacology and Molecular Science. He serves as a faculty member in the Cellular and Molecular Medicine Program at the Johns Hopkins School of Medicine and is a Professor of Chemical and Biomolecular Engineering in the Whiting School of Engineering at Johns Hopkins University.

Dr. Pienta has a proven track record in organizing and administering a translational research program that successfully incorporates bench research, agent development, and clinical application. Dr. Pienta is a two-time American Cancer Society Clinical Research Professor Award recipient. Between 1995-2013, Dr. Pienta was the Director of the Prostate Specialized Program of Research Excellence (SPORE) at The University of Michigan. Dr. Pienta was the Associate Vice President for Research, Health Sciences, for the University of the Michigan 2012-2013.

Currently, Dr. Pienta is involved in research to define the tumor microenvironment of prostate cancer metastases, as well as developing new therapies for prostate cancer. He is the author of more than 400 peer-reviewed articles, and been the principal investigator on numerous local and national clinical trials. Throughout his career, Dr. Pienta has effectively mentored more than 50 students, residents, and fellows to successful careers in medicine and science.

Peter Silvester

Peter Silvester

Senior Vice President and President, Life Sciences Solutions, Thermo Fisher Scientific

Peter Silvester was appointed Senior Vice President and President, Life Sciences Solutions in 2017. In this role, Peter provides executive oversight of Thermo Fisher Scientific’s Biosciences, Genetic Sciences and Clinical Next-Generation Sequencing businesses as well as Life Sciences Finance, Legal, HR, Licensing and Commercial Supply functions.

Peter’s experience covers many aspects of the life sciences industry including general management, manufacturing, and commercial strategy for technologies which help enable molecular diagnostics and targeted therapeutics for precision medicine. Peter created Thermo Fisher’s first team focused on establishing precision medicine partnerships, and since its inception continues to provide visionary direction for national program efforts across the globe.

Peter has more than 20 years of service with Thermo Fisher across different geographies and operating roles. Prior to his current role, Peter served for four years as President of the Biosciences business, formed following Thermo Fisher’s acquisition of Life Technologies in 2014. He has also served as President of Life Technologies’ Europe, Middle East and Africa (EMEA) region. In this role, Peter led the region through the integration of Invitrogen and Applied Biosystems and focused the team on developing the emerging markets in Russia, South Africa and the Middle East.

Peter was awarded a First Class Honors Degree from the University of Hertfordshire in Applied Biology. Prior to joining Thermo Fisher Scientific, Peter started his career in biotech leading the commercial organization and global distribution network for a DNA synthesis and therapeutics company.

Luis Lasalvia

Luis Lasalvia, MD, MIB

Vice President, Global Medical Officer, Siemens Healthineers

Dr. Luis Lasalvia achievements are driven by his strategic, clinical, and business leadership. Entrepreneur and strategist, Luis has a unique multi disciplinary experience and knowhow, covering several roles in clinical practice, pharmaceutical industry, consultancy/advisory, venturing, and medical devices. Speaker at approx. 500 conferences and events around the world, Luis also authored numerous papers in peer review journals, and submitted a number of patents in the US and Europe.

At Siemens Healthineers, as VP Global Medical Officer, he’s pursuing a modern and effective healthcare. Being a systemic thinker, his sharp focus on clinical and financial value runs across organizations and department levels. He is also leading the entire company wide thought leadership on precision medicine. By partnering with organizations and top thought leaders, Luis is enabling and providing guidance to executives around the globe.

Luis experience includes managing global partnerships, heading companywide Clinical mktg, leading critical multi-million commercial negotiations, running strategy and development of the precision medicine unit, managing strategic innovation, and scouting on business/clinical opportunities.

He’s a Medical Doctor from the Republic University in Montevideo, and holds a Master in International Business from Pompeu Fabra University in Barcelona. He holds postgraduate studies at The Wharton School of Business, New York University, and Harvard Business School.

Wendy Rubinstein

Wendy Rubinstein, MD, PhD, FACP, FACMG

Deputy Medical Director of CancerLinQ®, a not-for-profit subsidiary of the American Society of Clinical Oncology (ASCO).

Dr. Wendy Rubinstein is Deputy Medical Director of CancerLinQ®, a not-for-profit subsidiary of the American Society of Clinical Oncology (ASCO). CancerLinQ is ASCO’s physician-led web-based health information technology platform that collects and analyzes data from the electronic health records of participating practices across the United States to help improve the quality of care for patients with cancer.

Dr. Rubinstein directed academic cancer genetics programs for 15 years and has been a member of three NCI-designated Comprehensive Cancer Centers, most recently at the University of Chicago Medical Center. During her tenure as a Senior Scientist at the National Institutes of Health, Dr. Rubinstein launched and directed the NIH Genetic Testing Registry (GTR), now the most comprehensive publicly available information resource about genomic tests in the world. She served as Chief of Medical Genetics and Human Variation at the National Center for Biotechnology Information (NCBI) where she was responsible for flagship information resources including ClinVar, dbSNP, dbGaP, and GTR. Dr. Rubinstein was a representative to the NIH-FDA-CMS Trilateral Genomic Medicine Workgroup and FDA-NIH Interagency Task Force on Laboratory Developed Tests, and received the NIH Director’s Award from Dr. Francis Collins for developing and launching GTR.

An NIH Medical Scientist Training Program scholarship awardee, Dr. Rubinstein earned her MD and PhD at the Mount Sinai School of Medicine in New York City. She holds dual board certification in clinical genetics and clinical molecular genetics (ABMG) and is a Fellow of the American College of Medical Genetics (FACMG) and the American College of Physicians (FACP). A recognized expert in cancer genetics, she has authored and edited publications on gene discovery (SDHD), sequence variant interpretation, genomic population screening, computerized familial risk assessment, pharmacogenomics, genetic modifiers, genomic information resources, clinical guidelines, and health information technology.

Bob Vonderheide

Robert H. Vonderheide, MD, DPhil

Director, Abramson Cancer Center, Perelman School of Medicine and the John H. Glick, MD Abramson Cancer Center’s Director Professor at the University of Pennsylvania

Robert H. Vonderheide, MD, DPhil, is Director, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania and the John H. Glick, MD Abramson Cancer Center’s Director Professor. Dr. Vonderheide graduated from Oxford University as a Rhodes Scholar, and Harvard Medical School. He completed training in internal medicine and medical oncology at the Massachusetts General Hospital and the Dana Farber Cancer Institute. Dr. Vonderheide is a distinguished scientist and clinician who has deciphered mechanisms of cancer immune surveillance and developed novel cancer therapeutics, particularly in pancreatic cancer. He is well-recognized for driving the development of agonist CD40 antibodies, now in later stage clinical trials as potential immune therapy of cancer. Dr. Vonderheide discovered telomerase as a universal tumor antigen and has led the efforts to develop telomerase vaccination for both therapy and the prevention of cancer in healthy individuals. He has helped lead a team to show that stereotactic radiation therapy in combination with dual checkpoint blockade represents a synergistic path for immune activation in cancer. Dr. Vonderheide merges his clinical investigations with rigorous studies in mouse models or other laboratory systems. Dr. Vonderheide has been continuously funded by the NCI, and his high-impact findings have been published in Nature, Science, Cell and the New England Journal of Medicine.

Michael Joyner

Michael J. Joyner, M.D

Caywood Professor of Anesthesiology, Distinguished Investigator , Mayo Clinic

Michael J. Joyner, M.D., is the Caywood Professor of Anesthesiology at Mayo Clinic where he was named Distinguished Investigator in 2010. His research focuses on exercise physiology, human performance, blood pressure regulation, metabolism, and transfusion practices. He is also interested in the limits of scientific reductionism and the de-hyping of biomedical communications. The latter interest has led to a number of thought provoking and critical essays on the so-called Precision Medicine narrative in the popular press and key scientific journals. Professor Joyner attended the University of Arizona where he graduated with a B.S. in 1981 and an M.D. in 1987. After leaving Arizona he completed his residency training in anesthesiology at the Mayo Clinic in 1993 and then developed an independent research laboratory that has been funded by NIH since that time. His former fellows have established research programs at leading institutions throughout the world and he has held leadership positions at Mayo, in the extramural research community, and with leading journals.

Hannah Mamuszka

Richard Schilsky, MD, FACP, FASCO, FSCT

Senior Vice President and Chief Medical Officer (CMO) of ASCO

Dr. Schilsky is the Senior Vice President and Chief Medical Officer (CMO) of ASCO. He assumed this newly created position with the Society in February of 2013. Formerly the Chief of Hematology/Oncology in the Department of Medicine and Deputy Director of the University of Chicago Comprehensive Cancer Center, he is a highly respected leader in the field of clinical oncology. He specializes in new drug development and treatment of gastrointestinal cancers. Dr. Schilsky is a Past President of ASCO, having served in the role during 2008-2009, and also a Past Chair of one of the National Cancer Institute’s Cooperative Groups, Cancer and Leukemia Group B (CALGB).
Dr. Schilsky’s impressive experience and many accomplishments in both clinical medicine and clinical research reflect his deep passion for cancer medicine. Having served in prior leadership positions within ASCO, Dr. Schilsky has an in-depth understanding of the current trends and issues affecting oncology clinical practice. He has spent the majority of his career at the University of Chicago where he joined the faculty in 1984, subsequently rising to the rank of Professor of Medicine and serving in many roles, including Associate Dean for Clinical Research in the Biological Sciences Division and Director of the University of Chicago Cancer Research Center.
From 1995 to 2010, Dr. Schilsky served as chair of the Cancer and Leukemia Group B, a national cooperative clinical research group funded by the National Cancer Institute (NCI). He has extensive experience working with both the NCI and the Food and Drug Administration (FDA) having served as a member and chair of the NCI Board of Scientific Advisors, as a member of the NCI Clinical and Translational Research Committee, and as a member and chair of the Oncologic Drugs Advisory Committee of the FDA. Dr. Schilsky has served on the editorial boards of many cancer journals, including the Journal of Clinical Oncology. Most recently, he served as an Associate Editor of the Journal of the National Cancer Institute and Senior Associate Editor of Molecular Oncology, among other journals.
Early in his career, he worked in the Clinical Pharmacology Branch of the Division of Cancer Treatment at the NCI and was an Assistant Professor in the Department of Internal Medicine, Division of Hematology and Oncology at the University of Missouri-Columbia School of Medicine. He was also the head of the hematology/medical oncology unit at the Harry S. Truman Veterans’ Administration Hospital in Columbia, Missouri.

Erynn Gordon

Erynn Gordon, MS, LCGC

VP of Clinical Operations, Genome Medical

Erynn is a board-certified genetic counselor with expertise in clinical care, research and laboratory genetics. A leader in the genetic counseling community, Erynn has served as President of the American Board of Genetic Counseling and on the National Society of Genetic Counselors Board of Directors. Prior to joining Genome Medical, Erynn was the first genetic counselor at 23andMe, serving as Director of Clinical Affairs. She previously managed a precision medicine study at at the Coriell Institute for Medical Research and held clinical roles at University of Maryland School of Medicine and Children’s National Medical Center.

Ed Abrahams

Edward Abrahams, PhD

President, Personalized Medicine Coalition

Edward Abrahams, Ph.D., is the President of PMC. Representing innovators, scientists, patients, providers and payers, PMC promotes the understanding and adoption of personalized medicine concepts, services and products for the benefit of patients and the health system. It has grown from its original 18 founding members in 2004 to more than 200 today.

Previously, Dr. Abrahams was the Executive Director of the Pennsylvania Biotechnology Association, where he spearheaded the successful effort that led to the Commonwealth of Pennsylvania’s investment of $200 million to commercialize biotechnology in the state. Earlier, he had been Assistant Vice President for Federal Relations at the University of Pennsylvania and held a senior administrative position at Brown University.

Dr. Abrahams worked for seven years for the U.S. Congress, including as a legislative assistant to Senator Lloyd Bentsen, as an economist for the Joint Economic Committee under the chairmanship of Representative Lee Hamilton, and as a AAAS Congressional Fellow for Representative Edward J. Markey.

The author of numerous essays, Dr. Abrahams serves on the editorial board of Personalized Medicine and has also taught history and public policy at Brown University and the University of Pennsylvania.

Erynn is a board-certified genetic counselor with expertise in clinical care, research and laboratory genetics. A leader in the genetic counseling community, Erynn has served as President of the American Board of Genetic Counseling and on the National Society of Genetic Counselors Board of Directors. Prior to joining Genome Medical, Erynn was the first genetic counselor at 23andMe, serving as Director of Clinical Affairs. She previously managed a precision medicine study at at the Coriell Institute for Medical Research and held clinical roles at University of Maryland School of Medicine and Children’s National Medical Center.

Hannah Mamuszka

Katie Johansen Taber, PhD.

Director, Clinical Development, Myriad Women’s Health

Katherine (Katie) Johansen Taber, PhD is the Director of Clinical Development at the newly formed Myriad Women’s Health (formerly Counsyl). Her focus is on strategizing, designing, conducting, and publishing studies demonstrating the utility of prenatal and hereditary cancer risk screening in the women’s health setting. She additionally oversees a team working to maintain the clinical excellence of Myriad Women’s Health’s products and services. Before joining Counsyl/Myriad Women’s Health, she spent more than a decade at the American Medical Association, with a primary focus on educating physicians about the clinical implementation of genomics and precision medicine, and on identifying and managing genomics and precision medicine policy issues affecting health care providers. She has held numerous positions on advisory committees and boards of organizations working to improve clinical adoption of genomic technology, including a current appointment on the National Academy of Sciences, Engineering, and Medicine Roundtable on Genomics and Precision Health. Katie earned her PhD in Molecular, Cell, and Developmental Biology at the University of California, Los Angeles, and conducted post-doctoral research at the USDA. She has held teaching appointments at UCLA, California State Polytechnic University, University of Idaho, and Columbia College Chicago.

Hannah Mamuszka

John Quackenbush, PhD

Henry Pickering Walcott Professor of Computational Biology and Bioinformatics
Chair, Department of Biostatistics, Harvard University T.H. Chan School of Public Health

John Quackenbush is Professor of Computational Biology and Bioinformatics and Chair of the Department of Biostatistics at the Harvard TH Chan School of Public Health and Professor of Biostatistics and Computational Biology at the Dana-Farber Cancer Institute. John’s PhD was in Theoretical Physics, in 1992 he received a fellowship from the National Institutes of Health to work on the Human Genome Project, which led him from the Salk Institute to Stanford University to The Institute for Genomic Research (TIGR) before moving to Harvard in 2005. John’s research uses massive data from DNA sequencing and other assays to model functional networks in human cells. By comparing networks between groups of individuals, he has found new drug targets, explored chemotherapy resistance, and investigated differences between the sexes. He has made pioneering discoveries about how the genetic variants work together to determine our traits. John has published more than 280 papers; his work has been cited more than 65,000 times. He has received numerous awards for his work, including recognition in 2013 as a White House Open Science Champion of Change. He is also the co-founder of Genospace, a precision medicine software company that was purchased by the Hospital Corporation of America in 2017.

Jason Moore

Jason H. Moore, PhD, FACMI

Edward Rose Professor of Informatics,Director, Institute for Biomedical Informatics,Director, Division of Informatics,
Department of Biostatistics, Epidemiology, & Informatics,Senior Associate Dean for Informatics ,The Perelman School of Medicine University of Pennsylvania

Jason Moore is the Edward Rose Professor of Informatics and Director of the Penn Institute for Biomedical Informatics. He also serves as Senior Associate Dean for Informatics and Chief of the Division of Informatics in the Department of Biostatistics, Epidemiology, and Informatics. He came to Penn in 2015 from Dartmouth where he was Director of the Institute for Quantitative Biomedical Sciences. Prior to Dartmouth he served as Director of the Advanced Computing Center for Research and Education at Vanderbilt University where he launched their first high-performance computer. He has a Ph.D. in Human Genetics and an M.S. in Applied Statistics from the University of Michigan. He leads an active NIH-funded research program focused on the development of artificial intelligence and machine learning algorithms for the analysis of complex biomedical data. He is an elected fellow of the American Association for the Advancement of Science (AAAS), an elected fellow of the American College of Medical Informatics (ACMI), an elected fellow of the American Statistical Association (ASA), and was selected as a Kavli fellow of the National Academy of Sciences. He is currently Editor-in-Chief of the journal BioData Mining.

Hannah Mamuszka

Erica Ramos, MS, LCGC.

President, National Society of Genetic Counselors and Dir & Head of Clinical Business Development at Geisinger National Precision Health

Erica Ramos, MS, LCGC is Director and Head of Clinical & Business Development at Geisinger National Precision Health, a program built on the innovations of Geisinger’s MyCode Community Health Initiative leveraging genomics and electronic health data. At Geisinger National, Ramos is focusing on the development and implementation of clinical strategic partnerships to extend the Geisinger model on the national scene and accelerate the transition from research to clinical programs, at Geisinger and beyond. She is also the 2018 President of the National Society of Genetic Counselors, the leading professional organization for genetic counselors more than 3500 members strong. Prior to joining Geisinger, Ms. Ramos spent 11 years in patient care, then joined Illumina’s Clinical Services Laboratory in 2012, where she managed the clinical group that implemented interpretation and reporting processes for clinical whole genome sequencing (cWGS). As an Associate Director of Market Development at Illumina, she then focused on advancing the use of whole genome sequencing in clinical care, with a focus on predictive genomics and population health. She also tweets from @ERamosSD about genomics and genetic counseling, music, travel and other interests.

David Roth

David Roth, MD, PhD

Simon Flexner Professor and Chair of Pathology and Laboratory Medicine, Director, Penn Center for Precision Medicine, University of Pennsylvania Perelman School of Medicine

David B. Roth attended Rice University, obtained MD and PhD degrees from Baylor College of Medicine, and completed a residency in Anatomic Pathology at the National Cancer Institute. Roth joined the faculty of Baylor College of Medicine in 1993, and moved to New York University in 2001, where he served as Chair of the Department of Pathology and Director of the Medical Scientist Training Program. In 2011 Roth moved to the University of Pennsylvania as Chair of the Department of Pathology and Laboratory Medicine. At Penn, he founded the Center for Personalized Diagnostics, which was developed to bring genomic diagnostics to cancer patients. In 2016, he was named the Director of Penn’s new Center for Precision Medicine. His most recent research efforts are in applying principles of precision medicine to veterinary oncology, working with colleagues at Penn Vet.

Amy Miller

Amy M. Miller, PhD

President & CEO,  SWHR

Miller previously worked at the Personalized Medicine Coalition (PMC), where she served as Executive Vice President, working with innovators, scientists, providers and payers on scientific policy and business challenges impacting personalized medicine.

Before joining PMC, Miller worked in the office of the Director of the National Institute of Mental Health, where she served as a liaison among the scientific community, the legislative branch, and the consumers of mental health care and their families.

A former American Association for the Advancement of Science Fellow, Miller also served as a domestic policy advisor to Senator Jay Rockefeller. She began her career as a researcher at the National Institute of Child Health and Human Development.

Miller currently serves on the Editorial Board of Genome Magazine. She received a bachelor’s degree from the University of New Orleans and holds a doctoral degree in human development from the University of Connecticut.

Gary Palmer

Gary Palmer, MD

Chief Medical Officer, Tempus

Dr. Gary Palmer serves as Chief Medical Officer at Tempus, where he is responsible for leading clinical activities for the company and supporting external collaborations and strategic partnerships. Dr. Palmer most recently served as the Chief Medical Officer for NantHealth. Prior to his time there he served as Senior Vice President, Medical Affairs and Commercial Development at Foundation Medicine, where he helped launch the FoundationOne assay. Earlier in his career, Dr. Palmer served as the Chief of Medical Oncology at Mercy Health System, Sacramento and head of their Oncology Service Line. Prior to that he was as an Associate Professor of Medicine at University of California Davis Cancer Center. He earned a bachelor’s degree from Yale University, his medical degree from Stanford University School of Medicine and his masters of public health from the UCLA Fielding School of Public Health.

Hannah Mamuszka

Holli Hutcheson Dilks, Ph.D.

Director of Personalized Medicine Operations, Sarah Canon Research Institute

Holli Hutcheson Dilks, Ph.D. joined Sarah Cannon in 2014 as the Director of Personalized Medicine Operations. In this role, she is responsible for providing scientific support and direction for the development and implementation of Sarah Cannon’s global Molecular Profiling/Personalized Medicine Initiative. Additionally, she is responsible for the development of biomarker strategies in support of disease area programs and individual clinical trials.

Prior to joining Sarah Cannon, Dilks served as Technical Director of the Vanderbilt Technologies for Advanced Genomics Core Resource and Director of Core Resources at the Center for Human Genetics Research at Vanderbilt University Medical Center. She also served as a faculty member at Lipscomb University College of Pharmacy and a Program Director for SRI International based in Washington, D.C. Dilks received her B.A. from Lipscomb University, her Ph.D. in Molecular Physiology and Biophysics from Vanderbilt University, and performed her postdoctoral Cancer Research Training Award fellowship at the National Cancer Institute (NIH). During her fellowship, she served as a visiting scientist at the Broad Institute of MIT and Harvard. In addition to her role at Sarah Cannon, Dilks currently serves as an Adjunct Assistant Professor for the Department of Pharmaceutical Sciences at Lipscomb University College of Pharmacy.

Timothy Chan

Timothy A. Chan, MD, PhD

PaineWebber Chair in Cancer Genetics; Director, Immunogenomics and Precision Oncology Platform; Member, Human Oncology & Pathogenesis Program; Vice Chair, Department of Radiation Oncology; Director, Translational Oncology Division

I am Vice Chair of the Department of Radiation Oncology and Director of the Division of Translational Oncology. I am a board-certified radiation oncologist with a special interest in treating patients with brain tumors. I specialize in the use of stereotactic radiosurgery, intensity-modulated radiation therapy (IMRT), and conformal radiation therapy to treat both benign and malignant brain tumors precisely and effectively, while minimizing the effects of treatment on nearby healthy tissue. Among the diseases I treat are acoustic neuroma, meningioma, glioblastoma, anaplastic astrocytoma, low-grade glioma, oligodendroglioma, pituitary adenoma, and ependymoma.

I am a member of Memorial Sloan Kettering’s central nervous system disease management team, and I work closely with neurosurgeons and neuro-oncologists to provide optimal care for our patients. I am also a member of the Brain Tumor Center.
In addition to caring for patients, I am the principal investigator of a cancer genetics laboratory in the Human Oncology and Pathogenesis Program, where my colleagues and I are exploring the genetic changes that lead to cancer. We are dedicated to using our findings on the cancer genome to develop better diagnostic and treatment approaches that will improve the care of people with cancer.

Hannah Mamuszka

Nicholas Dracopoli, PhD

Dr. Klempner is a medical oncologist with a focus in gastrointestinal malignancies, oncogene driven tumors and clinical trials. His clinical and translational research is focused on cancer genomics, acquired resistance to targeted therapies and the intersection of genomics and immune mediated therapies to identify novel therapeutic approaches.

Dr. Klempner completed his residency in internal medicine at Brigham and Women’s Hospital/Harvard Medical School, followed by a combined hematology-oncology fellowship at Beth Israel Deaconess Medical Center/Harvard Medical School. While at Harvard Dr. Klempner studied the mechanisms of resistance to targeted therapies in tumor cells in the lab of Dr. Lewis Cantley, PhD. Dr. Klempner is board certified in medical oncology, hematology, and internal medicine. Prior to joining The Angeles Clinic and Research Institute Dr. Klempner served as an Assistant Clinical Professor in the division of Hematology-Oncology at the University of California Irvine. His research has been presented at major international meetings including the American Society of Clinical Oncology (ASCO), European Society of Medical Oncology (ESMO), the American Association for Cancer Research (AACR), and published in journals including the Journal of Clinical Oncology (JCO), Cancer Discovery, JAMA Oncology, Annals of Oncology and others. A complete list of publications can be found here.

Currently Dr. Klempner serves as the Director of Precision Medicine and GI Oncology at The Angeles Clinic and Research Institute. His ongoing research projects are focused in gastroesophageal malignancies.

Outside of the clinic Dr. Klempner enjoys woodworking, traveling with his wife, exercise, hunting, and spending time outside.

Hannah Mamuszka

Arturo Loaiza-Bonilla, MD, MSEd, FACP

Vice Chair, CTCA Department of Medical Oncology, CTCA Philadelphia

Dr. Arturo Loaiza-Bonilla is the current Vice Chair of Medical Oncology of Research at Cancer Treatment Centers of America – ERMC, and also Co-Founder and Chief Medical Officer at Massive Bio (www.massivebio.com). A precision oncology expert with experience at the Abramson Cancer Center of the University of Pennsylvania, University of Miami, Johns Hopkins and the National Institutes of Health, his major interest focuses in the field of innovative approaches to match oncology patients to phase 1-3 clinical and translational research cancer trials, integrating next-generation personalized molecular diagnostics, immunotherapy, biomarkers, previous therapies, and the patient’s overall status under an Artificial Intelligence-based and machine learning platform, which integrates to the electronic medical record. His company and virtual tumor board / clinical trial matching platforms have been recently featured in GenomeWeb and MedPage Today, including a first-in-the-world registry, SYNERGY-AI to match cancer patients based on Artificial Intelligence (https://clinicaltrials.gov/ct2/show/NCT03452774)

Dr. Loaiza-Bonilla is Principal and co-investigator on several Phase I/III clinical trials in several malignancies at Cancer Treatment Centers of America, with emphasis in new targeted therapies, novel molecules and immunotherapy, tailored to specific tumor type, its genomics and protein expression profiles. He is also a passionate advocate for improved access to medical care, precision oncology, medical education, organized medicine leadership and health policy, having been awarded the ‘Top 40 Under 40’ award by the Philadelphia Business Journal, AMA Foundation Leadership Award, Fellowship of the American College of Physicians, and holding a Master in Medical Education (M.S.Ed) degree from the University of Pennsylvania. He has held several leadership positions in state and medical societies, including his current tenure as executive board member of the Pennsylvania Society of Oncology and Hematology, and his role as President of the Board of Directors of the Global Alliance for Patient Access.

Eric Kmiec

Eric B Kmiec Ph.D.

Director, Gene Editing Program,Senior Research Scientist, Center for Translational Cancer Research, Helen F. Graham Cancer Center and Research Institute

Eric B. Kmiec, Ph.D., is well-known for his pioneering work in the fields of molecular medicine and gene editing. Throughout his professional career, Dr. Kmiec has led research teams in developing gene editing technologies and genetic therapies for inherited disorders such as Sickle Cell Disease. He is the recipient of multiple research awards from the National Institutes of Health (RO1s, R21s), the American Cancer Society, and private foundations including the 2012 Proudford Foundation Unsung Hero Award in Sickle Cell Disease. He has been a member of numerous editorial boards, NIH study sections and review boards and is the (primary/senior) author of more than 145 scientific publications (mostly in genetic recombination and gene editing).

He holds 18 issued patents, most of which have been licensed by biotechnology and pharmaceutical companies and has founded two biotechnology companies. He is a senior scientific advisor and SAB member of ETAGEN, a gene editing company located in Cambridge, Massachusetts, centered on the development of therapeutic uses of gene editing. Dr. Kmiec has been the primary mentor for 18 Ph.D. students and 4 MS students, all of whom have attained scientific positons. He has held or holds major administrative posts in various on NIH regional and state biomedical research grants, including IDeA Network of Biomedical Research (INBRE) and Centers of Biomedical Research Excellence (COBRE). Dr. Kmiec was also honored as the Eminent Scholar in residence at Marshall University (Huntington, West Virginia) in 2009-2011 and was elected as an Honorary Commander of the 436th Air Wing at Dover Air Force Base in Dover, Delaware for in 2013 and again in 2014.

The Gene Editing Institute, founded by Dr. Kmiec, is a core facility providing genetic tools for gene editing as well as instruction in the design and implementation of these tools for collaborators and colleagues nationwide. Currently, the Institute is working with a variety of groups within the Delaware/ IDeA state network and has recently developed an educational module for instruction of gene editing in undergraduate teaching laboratories. This module will be licensed, marketed and sold through an international biotechnology company.

Stephanie Devaney

Stephanie Devaney, Ph.D.

Deputy Director – All of Us Research Program, National Institutes of Health.

Stephanie Devaney is the Deputy Director of the All of Us Research Program at the National Institutes of Health. Prior to this she led the coordination of the Precision Medicine Initiative from the Office of the Chief of Staff at the White House. In this role she coordinated the many components of the Initiative and guided the vision of the overall effort, along with the many federal partners. Before joining the White House, Stephane worked in the Office of the Director at the National Institutes of Health. There she helped advance policies critical to biomedical research and the NIH mission and assisted in the development of programs and research initiatives to advance national scientific priorities, including the Precision Medicine Initiative. Prior to that, Stephanie was a researcher at the Genetics and Public Policy Center at Johns Hopkins University. There she conducted research on pharmacogenetics and drug labeling; performed a meta-analysis of non-invasive fetal gender genetic testing; and was involved in public engagement surrounding the many ethical and social issues that are emerging with novel genomic technologies. Stephanie received her Ph.D. in Molecular Genetics from the George Washington University and her B.S. in Biology from The Ohio State University.

Hannah Mamuszka

Richard D. Hammer, M.D.

Vice-Chair of Clinical Affairs, Department of Pathology & Anatomical Sciences, University of Missouri School of Medicine

Dr. Richard D. Hammer completed his undergraduate degree in Pharmacy from Duquesne University in Pittsburgh Pa., graduating Magna Cum Laude. While in Pharmacy school he gained experience in research in Medicinal Chemistry. He then was admitted to the elite combined M.D./Ph.D at the Medical University of South Carolina in Charleston, SC. where he studied pharmacology and the biochemistry of drug metabolism. He received his medical degree from the Medical University of South Carolina in Charleston, SC graduating in the top 10 in his class of 145. He then completed a 5 year-residency in Anatomic and Clinical Pathology at Vanderbilt University in Nashville TN. This was followed by a specialty year in Surgical Pathology and Cytology and then a two-year
fellowship in Hematopathology under Dr. Robert Collins, codeveloper of the Lukes-Collins lymphoma classification system. Dr. Hammer also spent an additional year of fellowship training in molecular pathology techniques with Dr. Cindy Vnencak-Jones at Vanderbilt developing novel molecular assays related to lymphomas. During his hematopathology training, Dr. Hammer was recipient of National Institute of Health training grant for three consecutive years with numerous publications, including defining papers describing splenic marginal zone lymphomas, immunocytochemistry of acute leukemias, cyclin D1, and NK/T cell leukemias. Dr. Hammer is board certified in Anatomic and Clinical Pathology with subspecialty board certification in Hematology.

Dr. Hammer is currently Vice Chair of Pathology and Anatomical Sciences at the University of Missouri. He is also Director of Hematopathology and Coagulation and Core Faculty at the MU Informatics Institute which has one of the largest graduate programs in medical informatics in the country. His research interests are in hematopathology, clinical decision support, translational bioinformatics and diagnostics, and imaging.

On a personal note, Dr. Hammer is an International referee in the World Drug Free Powerlifting Federation and holds the state record in Missouri for powerlifting. He also enjoys running and hiking and recently completed his first ultramarathon.

Hannah Mamuszka

Tara Schmidlen, MS, CGC

Clinical Investigator / Genetic Counselor – Geisinger Health System

Tara Schmidlen is a research genetic counselor with 12 years of experience in providing telephone-based genetic counseling for adult onset complex disease and pharmacogenomics, research biobanking and precision health research. She earned her Bachelor of Science degree in Biobehavioral Health from The Pennsylvania State University in 2002 and her Master of Science degree in Genetic Counseling from Arcadia University in 2006. She joined Geisinger in 2017 as a Clinical Investigator to further explore her research interests which center around the development of alternative genetic counseling service delivery models- particularly those that leverage the use of technology to facilitate communication with patients.

Hannah Mamuszka

Andrey Antov, PhD, MBA

Program Director, Maine Cancer Genomics Initiative, The Jackson Laboratory

Andrey is the Program Director for the MCGI. His healthcare professional experience includes basic research, medical device contracting and pharmaceutical; he has held a number of different roles from administration to consulting. Andrey holds a Ph.D in immunobiology and an M.B.A. in marketing and strategy from Yale University as well as a M.Sc. in biochemistry and a M.SC in ecology from The Sofia University in Bulgaria.
The Maine Cancer Genomics Initiative (MCGI) is the first-of-its-kind community-based genomic medicine program in Maine. Its goal is to deliver the very best precision cancer treatment across the entire state and further connect regional care centers with urban clinical trials for the best patient outcomes. The Initiative will cover the cost of genomic sequencing for 1,800 patients. Under the leadership of The Jackson Laboratory, patients at all Maine cancer practices are benefitting from the project. MCGI is filling the gap between innovation and implementation, providing education to clinicians and patients and, most importantly, making genomic testing accessible so that it can be adopted as a regular practice for Maine patients with cancers of varying complexity. https://www.jax.org/clinical-genomics/maine-cancer-genomics-initiative

Hannah Mamuszka

Charlene Son Rigby, MBA

Chief Business Officer, Fabric Genomics

Charlene Son Rigby is responsible for customer success, business development and regulatory at Fabric Genomics. Charlene has spent her career building businesses at the intersection of data, technology and life sciences. Previous to Fabric Genomics, she was responsible for all go-to-market activities at Metamarkets, a big data analytics startup acquired by Snap. Charlene was also Vice President of Business Planning at Oracle. She also led product management at DoubleTwist, a bioinformatics startup. Charlene started her career as a neuroscience researcher at Syntex (acquired by Roche). She holds a B.A. in Human Biology from Stanford University and an M.B.A. from the Haas School of Business at U.C. Berkeley.

Hannah Mamuszka

Ilan “Lanny” Kirsch, M.D.

Senior Vice President of Translational Medicine, Adaptive Biotechnologies

Dr. Kirsch received his M.D. from Harvard University Medical School and subsequently completed his Residency at Children’s Hospital Medical Center, Boston, Massachusetts and his Fellowship in Pediatric Hematology/Oncology at the National Cancer Institute (NCI) in Bethesda, Maryland. Dr. Kirsch also completed a three-year postdoctoral fellowship in molecular genetics in the laboratory of Dr. Philip Leder at the National Institute of Child Health and Human Development. Subsequently Dr. Kirsch spent over 20 years at the NCI as a basic researcher, attending physician, and, ultimately, Chief of the Genetics Branch within the Center for Cancer Research. In 2005 Dr. Kirsch joined the biotech/pharma company, Amgen, as an Executive Director heading the Oncology Research group at Amgen Washington in Seattle. During the next six years the Amgen Washington group was responsible for bringing a number of different therapeutic targets and modalities to Phase 1 trial evaluation. He currently serves as the Senior Vice President of Translational Medicine, Adaptive Biotechnologies, Seattle, Washington (www.adaptivebiotech.com). Adaptive Biotechnologies, a spin-out from the Fred Hutchinson Cancer Research Center, has developed a state-of-the-art platform of immunosequencing for the enumeration, specification, and quantification of each and every T- and/or B-cell in any sample of interest. Dr Kirsch is an author of more than 150 peer-reviewed manuscripts and over 30 books, chapters, or reviews.

David Nash

David B. Nash, MD, MBA

Dean Jefferson College of Population Health, Dr. Raymond C. & Doris N. Grandon Professor of Health Policy

Selin Kurnaz

Selin Kurnaz, Ph.D.

CEO – Massive Bio

Dr. Kurnaz is an expert in strategy, operations and transactions with a unique, global background that spans across healthcare, academia and consulting. After completing a PhD at the University of Michigan and receiving multiple engineering degrees, Dr. Kurnaz spent more than a decade delivering revenue enhancement, margin optimization and capital efficiency improvements for Pharmaceutical and Life Science companies. Dr. Kurnaz also has measurable success identifying and delivering value to over a dozen investment firms. Most recently, Dr. Kurnaz was with EY’s Private Equity Value Creation. Dr. Kurnaz has also written and spoke extensively about improving customer responsiveness in disruptive times.

Severance MacLaughlin

Severence MacLaughlin, PhD

Chief of Intelligence, VP – Artificial Intelligence and Data Sciences, Capgemini Invent

Severence serves as the Chief of Intelligence, Vice President – Artificial Intelligence & Data Scicences, of Capgemini Invent. Dr. MacLaughlin oversees and develops the sales, solutions and delivery of Systems of Intelligence that address complex corporate/organizational opportunities driving increased productivity, financial ROI as well as enhanced regulatory compliance in the verticals of Healthcare, Life Sciences, Banking & Financial Services, Oil &Gas, Natural Resources as well as Entertainment, Retail and Consumer Packaged Goods.
Dr. MacLaughlin is a thought leader in the application of Artificial Intelligence, Data Sciences & Advanced Analytics space and has helped numerous Healthcare (Payer, Provider, Technology & Government), Life Sciences (Pharma, Biotech & Medical Device) and Financial Services (Investment Banks, Hedge Funds, Private Equity and Venture Capital firms) organizations in addressing complex business challenges, resulting in improved health outcomes, better operational efficiencies, enhanced regulatory compliance, decreased costs and increased top line growth in an entrepreneurial fashion. He is well versed in Pharma operations from
development, clinical trials to regulatory and go to market events. In the Healthcare space, Severence is seen as a trusted advisor to the CXO’s in aiding digitization of Medical Operations for Hospitals and Providers as well as increasing health outcomes for the Payer Community.
Dr. MacLaughlin is one of the top ranked Life Sciences/Healthcare Data Scientists globally (Ranked among top 20 Life Sciences Data Scientists; Ranked #2 Healthcare Data Scientist; Ranked #1 Consulting Data Scientist in the Life Sciences and Healthcare knowledge base; Recognized as American Healthcare Leader for Q1 2018). Severence M. MacLaughlin’s career is comprised of a demonstrated track record in Artificial Intelligence, Data Sciences, Operational Strategic Analytics, BioIntelligence, Competitive Intelligence, Due Diligence and Project Execution for Healthcare, Life Science and Financial Services industries. Severence’s experiences encompass advising members of domestic and foreign governments on policy development for Technology Development (Artificial Intelligence), Healthcare, Life Sciences & Education (USA, UK, France, Australia, Russia & Kingdom of Denmark). In addition to these areas of expertise, Dr. MacLaughlin has interests in helping executive’s across a broad range of business sectors harness the true potential of their internal data sets to improve operational efficiency, rationalize costs and increase top line growth.
Severence has advised a diverse number of industries ranging from insurance, financial services, US auto sales, franchise based businesses, agriculture, academic institutions, and other Fortune 500 companies. Dr. Severence’s clients include advising the C suite of the top 25 global Health Care Insurance and Hospital Groups, the top 20 Pharma companies and two of the top Global Investment Banks. Severence manages the go-to-market, sales, solutioning and delivery of novel AI and data science accelerators in addition to advising and consulting executive integration and formulation of Data Sciences and Big Data Strategy Roadmap for these organizations. Dr. MacLaughlin has delivered over 40 new disruptive technologies and or implemented Systems of Intelligence resulting in over $1.8B in net present value to customers and an estimated $8B ROI over the next five years. In addition, Severence evaluates potential companies and technologies for acquisition and has developed a robust System for M&A and corporate restructuring activities encompassed within Due Diligence through Data Integrity (DDDI)
resulting in an increased rate of return on investment (RROI) & an improved process efficiency.
Prior to Capgemini Invent, Severence was the Global Head for Artificial Intelligence & Data Sciences in the Healthcare & Life Sciences verticals and Head, Artificial Intelligence Learning Institute (AILI) and Cognizant Academy of Data Sciences (CADS) at Cognizant Technology Solutions. Before his time at Cognizant, Dr. MacLaughlin served as Managing Director at MGI&I, where he brought to bear the power of data sciences  and advanced analytics fortelecom, automotive, healthcare, pharma and financial service clients (VC, PE, Hedge Funds) in terms of operational improvements, mergers & acquisitions and corporate restructuring.
Severence earned a BS (Magna Cum Laude, Honors & Distinction in Research) at Cornell University, a Doctorate Degree (Honors, Top 1%) from the University of Adelaide and a postdoctoral fellowship at the University of South Australia, where he maintains an adjunct academic position and taught medical, dental and nursing curricula. Severence has authored over 20 international scientific papers and given invited lectures and conference papers at academic
institutions as well as international scientific events. Severence is personally interested in equine, bovine and ovine genetics and breeding as well as being an accomplished equestrian and amateur polo player.

Yves Lussier

Yves Lussier, MD, FACMI

Associate Vice President for Health Sciences and Chief Knowledge Officer, Executive Director, Center for Biomedical Informatics and Biostatistics, University of Arizona Health Sciences

Dr. Lussier is the Associate Vice President for Information Science and Chief Knowledge Officer of the UA Arizona Health Sciences (UAHS), Founding Director of the Center for Biomedical Informatics and Biostatistics, and Professor of Medicine. He received a bachelor of engineering and his medical degree from the University of Sherbrooke, Quebec, Canada. He performed predoctoral research in the Departments of Medicine and Human Physiology at the University of Sherbrooke and then completed an internship in ophthalmology at Laval University Hospital in Quebec City, and a residency in family medicine at the University of Sherbrooke Medical Center. He was a post-doctoral residential fellow in the Department of Biomedical Informatics in the College of Surgeons & Physicians at Columbia University. Dr. Lussier’s research group conducts pioneering hypothesis-driven computational modeling predictions in precision medicine that are then validated in vitro, in vivo and in clinical trials. As a leader of the fields of translational bioinformatics and of Data Science-augmented precision medicine, he has launched successful companies and international conferences, authored 185 publications, and delivered more than 100 invited presentations in precision medicine, systems medicine, and translational bioinformatics, including 21 opening keynotes at international conferences. He has been awarded $190,000,000 in grants as principal, core leader, or co-investigator, and mentored 53 graduate and postgraduate students as well as 40 junior faculty members. Dr. Lussier’s honors include three IBM Faculty Awards, inducted Fellow of the American College of Medical Informatics (ACMI), 1st recipient of the Columbia University Faculty Mentoring Award, “Ambassador for Health Sciences” at the University of Sherbrooke (Canada), and 16 outstanding publication awards from the American Medical Informatics Association (AMIA), the International Society for Computational Biology (ISCB), and the Translational Bioinformatics Conference (TBC). In 2016, Dr. Lussier was invited among ten USA academic leaders invited by the White House for its Precision Medicine Summit, where the University of Arizona Center for Biomedical Informatics and Biostatistics that he directs has committed $20M of R&D in bringing precision medicine to practice.

Lorenz Mayr

Lorenz M. Mayr, Ph.D.

Chief Technology Officer (CTO), GE Healthcare Life Sciences

Since May 2017, Lorenz has been the Chief Technology Officer (CTO) for GE Healthcare Life Sciences and is responsible for all R&D investments, research programs, business growth strategy, technology innovation, and R&D talent development across all business areas (BioProcess, Imaging Diagnostics/Contrast Media, Research Tools and Applied Markets, Cell & Gene Therapy, New Opportunities).
Previously, he had been the Vice President & Global Head, Reagents & Assay Development with responsibility for generation of all biological reagents and assay development activities across all therapeutic research areas at AstraZeneca.
Before that, he was Executive Director at Novartis Pharma in Basel/Switzerland, at Bayer Pharma Research in Wuppertal/Germany, at Bayer Central Research in Leverkusen/Germany and at the M.I.T./Whitehead Institute in Cambridge/ Massachusetts (U.S.A.). He is lecturer for Biochemistry at the Martin-Luther University in Halle/Saale (Germany), has published over 60 papers in peer-reviewed journals and is member of several Scientific Advisory Boards (SABs).
He has received degrees in biochemistry, biophysics, molecular & cell biology at the University of Tubingen (Germany), University of Bayreuth (Germany) and the University of Colorado at Boulder (U.S.A.).

Lara Mangravite

Lara Mangravite, Ph.D.

President, Sage Bionetworks

Lara Mangravite, PhD is President of Sage Bionetworks, an organization that focuses on open practices to advance biomedicine through data-driven science and digital research. Recognizing that all research is limited by restrictions placed on the distribution of information, Sage works closely with institutes, foundations and research communities to improve information flow, benchmark research practices, and establish research outcomes of sufficient confidence to support translation. Dr. Mangravite obtained a BS in Physics from the Pennsylvania State University, a PhD in Pharmaceutical Chemistry from the University of California, San Francisco, and a postdoctoral fellowship in cardiovascular pharmacogenomics at the Children’s Hospital Oakland Research Institute.

Benjamin Haibe-Kains

Benjamin Haibe-Kains , Ph.D.

Senior Scientist, Princess Margaret Cancer Centre (PM), University Health Network, and Associate Professor in the Medical Biophysics Department of the University of Toronto

Dr. Benjamin Haibe-Kains is a Senior Scientist at the Princess Margaret Cancer Centre (PM), University Health Network, and Associate Professor in the Medical Biophysics department of the University of Toronto. Dr. Haibe-Kains earned his PhD in Bioinformatics at the Université Libre de Bruxelles (Belgium). Supported by a Fulbright Award, he did his postdoctoral fellowship at the Dana-Farber Cancer Institute and Harvard School of Public Health (USA). He started his own laboratory at the Institut de Recherches Cliniques de Montréal (Canada) and moved to PM in November 2013. Dr. Haibe-Kains’ research focuses on the integration of high-throughput data from various sources to simultaneously analyze multiple facets of carcinogenesis. In particular, Dr. Haibe-Kains and his team are analyzing radiological and (pharmaco)genomic datasets to develop new prognostic and predictive models and to discover new therapeutic regimens with the aim to significantly improve disease management. Dr. Haibe-Kains’ main scientific contributions include several prognostic gene signatures in breast cancer, subtype classification models for ovarian and breast cancers, genomic predictors of drug response in cancer cell lines, and radiomic prognostic models in head-and-neck cancers.

Leslie Bucheit

Leslie Bucheit MS, CGC

Product Manager, Digital Products, Myriad Genetics

Leslie Bucheit, MS, CGC is a certified genetic counselor with experience in product management, clinical program development, and hereditary cancer. A graduate of the University of Cincinnati Genetic Counseling Program, Leslie has experience in both patient care and industry settings. Across roles, Leslie has sought to increase access to care, implement novel service delivery models, and leveraged technology to scale genetic counseling and testing services. She currently works as a Product Manager for digital products at Myriad Genetics following the acquisition of Counsyl where she focuses on identifying and developing digital workflow solutions to enable genetic testing to be part of routine clinical practice. Leslie has served in various leadership roles at local, state, and national genetics organizations including NSGC and CAGIGC. Leslie tweets from @gcleslieb about hereditary cancer, service delivery, leadership values, and the importance of diversity in the worksplace. She resides in Cincinnati, Ohio with her husband and two children.

Michael Cantor

Michael Cantor, MD, MA

Executive Director, Clinical Informatics, Regeneron Genetics Center

Michael N. Cantor, MD, MA is Executive Director, Clinical Informatics , at the Regeneron Genetics Center. Currently his work focuses on developing and optimizing phenotypes from EHR data and linking them with genetic data to help discover new drug targets. Prior to Regeneron, he was Director of Clinical Research Informatics at New York University School of Medicine. As Director of Clinical Research Informatics, he was also the clinical director for NYULH’s DataCore, where his work focused on data management for clinical trials, using data from clinical systems to research, and advanced analytics. His research interests include integrating and standardizing social determinants of health-related data into the EHR, optimizing informatics systems for clinical trials, and providing self-service data access tools for researchers. During his previous tenure at NYU, Dr. Cantor was the Chief Medical Information Officer for the South Manhattan Healthcare Network of the New York City Health and Hospitals Corporation, based at Bellevue, and saw patients and precepted at the medical clinic there. Dr. Cantor completed his residency in internal medicine and informatics training at Columbia, has an M.D. from Emory University, and an A.B. from Princeton, and is an Associate Professor in the Department of Medicine at NYU School of Medicine. He currently sees patients weekly at Bellevue’s medicine clinic

Phil Empey

Philip Empey, PharmD, PhD

Associate Director, Institute of Precision Medicine, University of Pittsburgh and UPMC.

Dr. Philip Empey is the Associate Director of the Institute of Precision Medicine at the University of Pittsburgh and UPMC. He directs the Pharmacogenomics Center of Excellence and leads the PreCISE-Rx and Test2Learn teams to implement pharmacogenomics clinical, research, and educational initiatives. As a clinician-scientist in the Department of Pharmacy and Therapeutics of the School of Pharmacy, Dr. Empey conducts NIH-funded clinical and translational research aimed at understanding the mechanisms of the variability in drug response to improve medication-related outcomes in critically-ill patients. His research interests include large scale population preemptive testing, pharmacogenomics clinical implementation, collection of medication-related phenotype information, genotype-phenotype discovery, and understanding the role/impact of xenobiotic transporters following neurological injury. Dr. Empey received his PharmD from the University of Rhode Island and completed PGY1 and PGY2 residencies in Pharmacy Practice and Critical Care at the University of Kentucky. He earned a PhD in Clinical Pharmaceutical Sciences at the University of Kentucky before completing postdoctoral research training at the University of Pittsburgh.

SPONSORS

Myriad Women's Health

PARTNERS

Novartis

VENUE

Smilow Center for Translational Research

Rubenstein Auditorium

3400 Civic Center Boulevard
Philadelphia, Pennsylvania 19104
United States
(215) 573-6784

Smilow Center for Translational Research

There are numerous options for accommodation while attending the event. Please utilize your  regular resources for travel and accommodation. The Precision Medicine Leaders’ Summit, Kneed Media, or the University of Pennsylvania do not engage with any third parties to provide assistance for accommodation or travel.

As you are probably aware there are numerous entities that may approach you to book your travel and accommodation, please ignore these solicitations as they are in no way associated with the Precision Medicine Leaders’ Summits.

There is limited parking available at the event venue.

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